Cerebral aneurysms: risk factors for formation
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cerebral aneurysms: risk factors for formation. Smoking, Hypertension, Alcohol. Fully referenced neurology checklist.
Acquired risk factors
- Smoking
- Hypertension
- Alcohol
- Possibly oral contraceptive pills (OCPs)
- Previous aneurysm: especially in women and familial aneurysms
- Hypothyroidism
- HIV associated vasculopathy: with multiple aneurysms
- Cervical artery tortuosity
- Coronary artery disease seems protective
- Low bone mineral density
- Low magnesium levels
Familial risk factors
Locked: subscribe to see this section.
Adult polycystic kidney disease (APCKD)
Locked: subscribe to see this section.
Other connective tissue disorders
Locked: subscribe to see this section.
Candidate genes
Locked: subscribe to see this section.
Risk factors for multiple aneurysms
Locked: subscribe to see this section.
References
- Rinkel GJE. Intracranial aneurysm screening: indications and advice for practice. Lancet Neurol 2005; 4:122-128.
- Lai LT, Morgan MK, Patel NJ. Smoking increases the risk of de novo intracranial aneurysms. World Neurosurg 2014; 82:e195-e201.
- Atchaneeyasakul K, Tipirneni A, Zhang T, et al. Association of hypothyroidism with unruptured cerebral aneurysms: a case-control study. J Neurosurg 2017; 17:1-4.
- Goldstein DA, Timpone J, Cupps TR. HIV-associated intracranial aneurysmal vasculopathy in adults. J Rheumatol 2010; 37:226-233.
- Tipping B, de Villiers L, Candy S, Wainwright H. Stroke caused by human immunodeficiency virus-associated intracranial large-vessel aneurysmal vasculopathy. Arch Neurol 2006; 63:1640-1642.
- And 22 more. Subscribe to see the full list
