Cerebral aneurysms: aneurysm-related risk factors for rupture

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cerebral aneurysms: aneurysm-related risk factors for rupture. Familial aneurysms have a higher risk of ruptured than sporadic.

Familial aneurysms

  • Familial aneurysms have a higher risk of ruptured than sporadic
  • This is especially if there is a first-degree family history of aneurysm or SAH

Aneurysm size

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Aneurysm size ratio (SR)

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Aneurysm shape

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Aneurysm high-risk locations

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Aneurysm infection

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Aneurysm wall enhancement (AWE)

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Other rupture risk factors

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The ELAPSS score for predicting risk of aneurysm rupture

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References

  1. Clarke M. Systematic review of reviews of risk factors for intracranial aneurysms. Neuroradiology 2008; 50:653-664.
  2. Thompson BG, Brown RD Jr, Amin-Hanjani S, et al. American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, and Council on Epidemiology and Prevention; American Heart Association; American Stroke Association. Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2015; 46:2368-2400. 
  3. Juvela S, Poussa K, Lehto H, Porras M. Natural history of unruptured intracranial aneurysms: a long-term follow-up study. Stroke 2013; 44:2414-2421.
  4. Ishibashi T, Murayama Y, Urashima M, Saguchi T, Ebara M, Arakawa H, Irie K, Takao H, Abe T. Unruptured intracranial aneurysms: incidence of rupture and risk factors. Stroke 2009; 40:313-316.
  5. Broderick JP, Brown RD Jr, Sauerbeck L, et al; FIA Study Investigators. Greater rupture risk for familial as compared to sporadic unruptured intracranial aneurysms. Stroke 2009; 40:1952-1957.
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