Cerebral amyloid angiopathy (CAA): treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cerebral amyloid angiopathy (CAA): treatment. Intensive care unit for initial management. Fully referenced neurology checklist.
Preventative treatment of haemorrhage
- Intensive care unit for initial management
- Avoid straining: this increases the risk of bleeding
- Venous thrombosis prophylaxis
- Maintain normoglycaemia
Treatment of associated coagulopathy
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Treatments to limit haematoma expansion
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Other treatments
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Investigational treatments
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References
- Mehndiratta P, Manjila S, Ostergard T, Eisele S, Cohen ML, Sila C, Selman WR. Cerebral amyloid angiopathy-associated intracerebral hemorrhage: pathology and management. Neurosurg Focus 2012; 32:E7.
- Charidimou A, Gang Q, Werring DJ. Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum. JNNP 2012; 83:124-137.
- Regenhardt RW, Thon JM, Das AS, et al. Association between immunosuppressive treatment and outcomes of cerebral amyloid angiopathy-related inflammation. JAMA Neurol 2020; 77:1261-1269.
- Snorradottir AO, Gutierrez-Uzquiza A, Bragado P, et al. N-acetylcysteine for hereditary cystatin C amyloid angiopathy: a nonrandomized clinical trial. JAMA Neurol 2025; 82:486-494.
