Cerebral amyloid angiopathy (CAA): investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cerebral amyloid angiopathy (CAA): investigations. If familial and age <50 years. Fully referenced neurology checklist.
Genetic testing
- If familial and age <50 years
Magnetic resonance imaging (MRI)
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Amyloid biomarkers: A beta and tau
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CT or MR angiography
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Pathology
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References
- Cordonnier C, Klijn C, Smith EE, et al. Diagnosis and management of cerebral amyloid angiopathy: a scientific statement from the International CAA Association and the World Stroke Organization. Int J Stroke 2025; 20:949-967.
- Li Q, Zanon Zotin MC, Warren AD, et al. Perivascular space progression in patients with cerebral amyloid angiopathy. Eur Neurol 2026; 89:75-82.
- Rannikmae K, Samarasekera N, Martinez-Gonzalez NA, Al-Shahi Salman R, Sudlow CLM. Genetics of cerebral amyloid angiopathy: systemic review and meta-analysis. JNNP 2013; 84:901-908.
