Castleman’s disease
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Castleman’s disease. This is angiofollicular hyperplasia of lymph nodes. It is a lymphoproliferative disorder. Fully referenced neurology checklist.
Pathology
- This is angiofollicular hyperplasia of lymph nodes
- It is a lymphoproliferative disorder
Pathological types
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Haematological features
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Locations of extra-nodal masses
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Neurological features
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Types: Castleman’s disease without POEMS syndrome (CD-PN)
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Types: Castleman’s disease with POEMS syndrome (CD-POEMS)
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Differential diagnosis of Castleman’s disease
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Treatment
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References
- Yu H, Yao F, Li Y, Li J, Cui QC. Castleman disease variant of POEMS syndrome complicated with multiple cerebral infarction: a rare case report and review of literature. Int J Clin Exp Pathol 2015; 8:13578-13583.
- Riccio A, Natale D, Pettinato G, Sparano L, Petto A, Puzziello A. Castleman's disease. Ann Rheum Dis 2001; 60:176.
- Smith C, Lee-Miller C, Dishop MK, Cost C, Wang M, Asturias EJ. Multicentric Castleman disease presenting with fever. J Pediatr 2014; 165:1261-1265.
- Eward WC, DeWitt SB, Brigman BE, Kontogeorgakos V, Lagoo AS. Extranodal Castleman disease of the extremities: a case report and review of the literature. Skeletal Radiol 2014; 43:1627-1631.
- Garcia T, Dafer R, Hocker S, Schneck M, Barton K, Biller J. Recurrent strokes in two patients with POEMS syndrome and Castleman's disease. J Stroke Cerebrovasc Dis 2007; 16:278-284.
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