Carney complex (CNC)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Carney complex (CNC). This is a familial lentiginosis. Fully referenced neurology checklist.
Genetics
- This is a familial lentiginosis
- It is caused by mutations or deletions in the PRKAR1A gene on chromosome 17q
- The gene codes for type I alpha of protein kinase A (PKA)
- The transmission is autosomal dominant
Major tumours and lesions
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Systemic adenomas
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Other tumours
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Skin and mucosal lesions
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Previous designated acronyms: LAMB
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