Carbon monoxide (CO) leukoencephalopathy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Carbon monoxide (CO) leukoencephalopathy. This causes a delayed post-hypoxic leukoencephalopathy. Fully referenced neurology checklist.
Clinical features
- This causes a delayed post-hypoxic leukoencephalopathy
- It presents with rapidly progressive cognitive impairment
- There are behavioral deficits
- There may be associated akinetic mutism
- Parkinsonism may be a feature
Magnetic resonance imaging (MRI): features
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Other neurological features
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Systemic features
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Hyperbaric oxygen treatment: indications
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References
- Prockop LD, Chichkova RI. Carbon monoxide intoxication: an updated review. J Neurol Sci 2007; 262:122-130.
- Geraldo AF, Silva C, Neutel D, Neto LL, Albuquerque L. Delayed leukoencephalopathy after acute carbon monoxide intoxication. J Radiol Case Rep 2014; 8:1-8.
- Varrassi M, Di Sibio A, Gianneramo C, et al. Advanced neuroimaging of carbon monoxide poisoning. Neuroradiol J 2017; 30:461-469.
- Mizuno Y, Sakurai Y, Sugimoto I, et al. Delayed leukoencephalopathy after carbon monoxide poisoning presenting as subacute dementia. Intern Med 2014; 53:1441-1445.
- Geraldo AF, Silva C, Neutel D, Neto LL, Albuquerque L. Delayed leukoencephalopathy after acute carbon monoxide intoxication. J Radiol Case Rep 2014; 8:1-8.
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