Brain tumours: risk factors
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Brain tumours: risk factors. Tuberous sclerosis, Neurofibromatosis 1 and 2 (NF1 and NF2). Fully referenced neurology checklist.
Genetic risk factors
- Tuberous sclerosis
- Neurofibromatosis 1 and 2 (NF1 and NF2)
- Neavoid basal cell carcinoma syndrome
- Adenomatous polyposis
- Folate metabolism gene polymorphisms: risk of meningiomas and gliomas
- SMARCB1/INI1 gene mutations
- L-2-hydroxyglutaric aciduria (L2HGDH) gene mutations
Chemical and environmental risk factors
Locked: subscribe to see this section.
Individual risk factors
Locked: subscribe to see this section.
Other risk factors
Locked: subscribe to see this section.
Mobile phone use
Locked: subscribe to see this section.
Factors which do not increase the risk of brain tumours
Locked: subscribe to see this section.
Factors which may reduce the risk of brain tumours
Locked: subscribe to see this section.
References
- Wigertz A, Lonn S, Mathiesen T, et al. Risk of brain tumors associated with exposure to exogenous female sex hormones. Am J Epidemiol 2006; 164:629-636.
- Wrensch M, Minn Y, Chew T, Bondy M, Berger MS. Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol 2002; 4:278-299.
- Bethke L, Webb E, Murray A, et al. Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma. Cancer Epidemiol Biomarkers Prev 2008; 17:1195-1202.
- Zhang J, Zhou YW, Shi HP, Wang YZ, Li GL, Yu HT, Xie XY. 5,10-Methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTRR), and methionine synthase reductase (MTR) gene polymorphisms and adult meningioma risk. J Neurooncol 2013; 115:233-239.
- Kohashi K, Oda Y. Oncogenic roles of SMARCB1/INI1 and its deficient tumors. Cancer Sci 2017; 108:547-552.
- And 21 more. Subscribe to see the full list
