Anti Ma2 antibody paraneoplastic syndrome: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti Ma2 antibody paraneoplastic syndrome: clinical features. Limbic encephalitis, Diancephalic epilepsy. Fully referenced neurology checklist.
Central phenotypes
- Limbic encephalitis
- Diancephalic epilepsy
- Brainstem encephalitis
- Subacute cerebellar degeneration (SCD)
- Myeloradiculopathy
- Progressive spastic paraparesis
Peripheral phenotypes
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Encephalitis
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Eye movement disorders
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Movement disorders
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Sleep disorders
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Psychiatric disorders
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Other features
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Differential diagnosis
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References
- Dalmau J, Graus F, Villarejo A, et al. Clinical analysis of anti-Ma2-associated encephalitis. Brain 2004; 127:1831-1844.
- Kraker J. Treatment of anti-Ma2/Ta paraneoplastic syndrome. Curr Treat Options Neurol 2009; 11:46-51.
- Rosenfeld MR, Dalmau J. Update on paraneoplastic neurologic disorders. Oncologist 2010; 15:603-617.
- Murphy SM, Khan U, Alifrangis C, et al. Anti Ma2-associated myeloradiculopathy: expanding the phenotype of anti-Ma2 associated paraneoplastic syndromes. JNNP 2012; 83:232-233.
- Piccolo G, Tavazzi E, Jarius S, et al. Anti-Ma2/Ta antibodies in a woman with primary lateral sclerosis-like phenotype and Sjögren syndrome. Neurol Sci 2011; 32:915-917.
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