Amyloid myopathy: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Amyloid myopathy: management. Creatinine kinase (CK): this is normal in 50% of cases. Fully referenced neurology checklist.
Blood and urine tests
- Creatinine kinase (CK): this is normal in 50% of cases
- Cardiac troponin T: this is elevated without heart disease
- Free light chains in serum and urine
Magnetic resonance imaging (MRI) muscle
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Muscle biopsy: features
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Other biopsies for amyloid myopathy
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Test for amyloidosis
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Treatment
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References
- Muchtar E, Derudas D, Mauermann M, et al. Systemic immunoglobulin light chain amyloidosis-associated myopathy: presentation, diagnostic pitfalls, and outcome. Mayo Clin Proc 2016; 91:1354-1361.
- Gertz MA, Kyle RA. Myopathy in primary systemic amyloidosis. JNNP 1996; 60:655-660.
- Hull KM, Griffith L, Kuncl RW, Wigley FM. A deceptive case of amyloid myopathy: clinical and magnetic resonance imaging features. Arthritis Rheum 2001; 44:1954-1958.
- Metzler JP, Fleckenstein JL, White CL 3rd, Haller RG, Frenkel EP, Greenlee RG Jr. MRI evaluation of amyloid myopathy. Skeletal Radiol 1992; 21:463-465.
- Okamoto K, Ito J, Emura I, Kawasaki T, Furusawa T, Sakai K, Tokiguchi S. Focal orbital amyloidosis presenting as rectus muscle enlargement: CT and MR findings. Am J Neuroradiol 1998; 19:1799-1801.
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