Acute disseminated encephalomyelitis (ADEM): differential diagnosis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Acute disseminated encephalomyelitis (ADEM): differential diagnosis. Multiple sclerosis (MS). Fully referenced neurology checklist.
Inflammatory differentials
- Multiple sclerosis (MS)
- Neuromyelitis optica (NMO)
- Neurosarcoidosis
Autoimmune differentials
Locked: subscribe to see this section.
Infective differentials
Locked: subscribe to see this section.
Metabolic differentials
Locked: subscribe to see this section.
Malignant differentials
Locked: subscribe to see this section.
Other differentials
Locked: subscribe to see this section.
Features suggestive of MS over ADEM
Locked: subscribe to see this section.
Features suggestive of ADEM over MS
Locked: subscribe to see this section.
References
- Pohl D, Alper G, Van Haren K, et al. Acute disseminated encephalomyelitis: updates on an inflammatory CNS syndrome. Neurology 2016; 87(9 Suppl 2):S38-S45.
- Duman Ö, Yürekli VA, Gencpinar P, et al. Unusual clinical cases that mimic acute disseminated encephalomyelitis. Acta Clin Croat 2015; 54:371-377.
- Rodríguez-Fernández C, López-Marín L, López-Pino MÁ, Gutiérrez-Solana LG, Soto-Insuga V, Conejo-Moreno D. Analysis of a series of cases with an initial diagnosis of acute disseminated encephalomyelitis over the period 2000-2010. Rev Neurol 2013; 57:297-305.
- Otowa Y, Yamakawa I, Ogawa N, et al. Amoebic encephalitis mimicking acute disseminated encephalomyelitis. Pract Neurol 2021; 21:433-434.
- Arenson NE, Heydemann PT. Late-onset Krabbe's disease mimicking acute disseminated encephalomyelitis. Pediatr Neurol 2005; 33:208-210.
- And 4 more. Subscribe to see the full list
