Wilson’s disease: monitoring and prognosis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Wilson’s disease: monitoring and prognosis. Serum copper and ceruloplasmin, Liver biochemistry, Full blood count. Fully referenced neurology checklist.
Twice annual monitoring indices
- Serum copper and ceruloplasmin
- Liver biochemistry
- Full blood count
- Urinalysis
- Physical examination
Annual 24-hour urinary excretion
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Indicators of over-treatment
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Indicators of treatment non-adherence
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Clinical rating scales
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Poor prognostic factors
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References
- Roberts EA, Schilsky ML. Diagnosis and treatment of Wilson disease: an update. Hepatology 2008; 47:2089-2111.
- Bandmann O, Weiss KH, Kaler SG. Wilson’s disease and other neurological copper disorders. Lancet Neurol 2015; 14:103-113.
- Volpert HM, Pfeiffenberger J, Gröner JB, et al. Comparative assessment of clinical rating scales in Wilson's disease. BMC Neurol 2017; 17:140.
- Lorincz MT. Neurologic Wilson’s disease. Ann N Y Acad Sci 2010; 1184:173-187.
