Whipple’s disease: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Whipple’s disease: clinical features. Oculomasticatory myorrhythmia (OMM), Ataxia, Myoclonus, Chorea, Dystonia. Fully referenced neurology checklist.
Movement disorders
- Oculomasticatory myorrhythmia (OMM)
- Ataxia
- Myoclonus
- Chorea
- Dystonia
Cognitive features
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Sleep disorders
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Other central neurological features
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Peripheral neurological features
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Ophthalmic features
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Systemic features
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Differential diagnosis of CNS Whipple’s disease
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References
- Panegyres PK, Efis R, Beaman M, Fallon M. Primary Whipple's disease of the brain: characterization of the clinical syndrome and molecular diagnosis. Q J Med 2006; 99:609-623.
- Panegyres PK. Diagnosis and management of Whipple's disease of the brain. Pract Neurol 2008; 8:311-317.
- Palma JA, Luquin MR, Riverol M, et al. Primary Whipple disease of the CNS presenting with chorea and dystonia: A video case report. Neurol Clin Pract 2014; 4:508-510.
- Manini A, Querzola G, Lovati C, Pantoni L. Rapidly progressive dementia and intractable diarrhea: a teaching case report and a systematic review of cognitive impairment in Whipple's disease. Neurol Sci 2022; 43:907-926.
- Pessa ME, Baldi A, Gigli GL, Valente M. A case of rapidly progressive dementia: Whipple disease of CNS. Neurol Sci 2018; 39:591-592.
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