West syndrome: clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

West syndrome: clinical features. These are myoclonic-tonic seizures. Fully referenced neurology checklist.

Clinical features: infantile spasms

  • These are myoclonic-tonic seizures
  • They manifest as sudden bilateral flexion, extension, or both
  • They involve the neck, body, and limbs
  • They usually resolve by the age of 5 years

Clinical features: others

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Mortality

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Electroencephalography (EEG)

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References

  1. Salar S, Moshé SL, Galanopoulou AS. Metabolic etiologies in West syndrome. Epilepsia Open 2018; 3:134-166. 
  2. Wheless JW, Gibson PA, Rosbeck KL, et al. Infantile spasms (West syndrome): update and resources for pediatricians and providers to share with parents. BMC Pediatr 2012; 12:108. 
  3. Kural Z, Ozer AF. Epileptic encephalopathies in adults and childhood. Epilepsy Res Treat 2012; 2012:205131.
  4. Lagae L, Verhelst H, Ceulemans B, et al. Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study. Seizure 2010; 19:159-164.
  5. Sillanpää M, Riikonen R, Saarinen MM, Schmidt D. Long-term mortality of patients with West syndrome. Epilepsia Open 2016; 1:61–66.

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