Warfarin: switching to new oral anticoagulants
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Warfarin: switching to new oral anticoagulants. Inadequate time on therapeutic range (TTR) of INR. Fully referenced neurology checklist.
Indications to switch
- Difficulty instituting safe monitoring of international normalised ratio (INR)
- Inadequate time on therapeutic range (TTR) of INR
- Stroke developing whilst on adequate INR
- Patient preference
- Concurrent use of Warfarin-interacting drugs
Process of switching
Locked: subscribe to see this section.
Switching to Warfarin from new anticoagulants
Locked: subscribe to see this section.
References
- Kirchhof P, Lip GYH, Van Gelder IC, et al. Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options- a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference. Europace 2012; 14:8-27.
- Agarwal MB, Verma S, Mahapatra M, et al. Balancing efficacy and bleeding risk in the prevention of stroke due to atrial fibrillation with newer oral anticoagulants. Indian J Hematol Blood Transfus 2012; 28:129-143.
- Weimer C, Hohnloser SH, Eikelboom JW, Diener H-C. Preventing cardioembolic stroke in atrial fibrillation with dabigatran. Curr Neurol Neurosci Rep 2012; 12:17-23.
