Vitamin B12 deficiency: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Vitamin B12 deficiency: clinical features. This is usually sudden onset. Fully referenced neurology checklist.
Peripheral axonal neuropathy (PN)
- This is usually sudden onset
- It usually starts in the upper limbs or simultaneously in the upper and lower limbs
- It is mainly painless and sensory
Movement disorders
Locked: subscribe to see this section.
Neuropsychiatric disorders
Locked: subscribe to see this section.
Other neurological disorders
Locked: subscribe to see this section.
Dermatological features
Locked: subscribe to see this section.
Haematological features
Locked: subscribe to see this section.
Other features
Locked: subscribe to see this section.
References
- Reynolds E. Vitamin B12, folic acid and the nervous system. Lancet Neurol 2006; 5:949-960.
- Overell JR. Peripheral neuropathy: pattern recognition for the pragmatist. Pract Neurol 2011; 11:62-70.
- Hemmer B, Glocker FX, Schumacher M, Deuschl G, Lucking CH. Subacute combined degeneration: clinical, electrophysiological, and magnetic resonance findings. JNNP 1998; 65:822-827.
- Zanus C, Alberini E, Costa P, Colonna F, Zennaro F, Carrozzi M. Involuntary movements after correction of vitamin B12 deficiency: a video-case report. Epileptic Disord 2012; 14:174-180.
- Kumar S. Vitamin B12 deficiency presenting with an acute reversible extrapyramidal syndrome. Neurol India 2004; 52:507-509.
- And 27 more. Subscribe to see the full list
