Tumefactive demyelination (TD): causes
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Tumefactive demyelination (TD): causes. Demyelinating lesions ≥2 cm or. Fully referenced neurology checklist.
Definition
- Demyelinating lesions ≥2 cm or
- Demyelinating lesions between 0.5-2 cm with mass effect
Inflammatory
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Neoplastic
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Vascular
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Infectious
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Paraneoplastic: antibodies
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Acronym
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References
- Algahtani H, Shirah B, Alassiri A. Tumefactive demyelinating lesions: a comprehensive review. Mult Scler Relat Disord 2017; 14:72-79.
- Lucchinetti CF, Gavrilova RH, Metz I, et al. Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis. Brain 2008; 131:1759-1775.
- Hardy TA, Chataway J. Tumefactive demyelination: an approach to diagnosis and management. JNNP 2013; 84:1047-1053.
- Nakayama M, Naganawa S, Ouyang M, Jones KA, Kim J, Capizzano AA, Moritani T. A review of clinical and imaging findings in tumefactive demyelination. Am J Roentgenol 2021; 217:186-197.
- Lin X, Yu W-Y, Liauw L, et al. Clinicoradiologic features distinguish tumefactive multiple sclerosis from CNS neoplasms. Neurol Clin Pract 2017; 7:53-64.
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