Transient loss of consciousness (TLOC): causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Transient loss of consciousness (TLOC): causes. Hypertrophic cardiomyopathy. Fully referenced neurology checklist.

Cardiac causes

  • Hypertrophic cardiomyopathy
  • Arrhythmogenic right ventricular dysplasia
  • Severe ischemic left ventricular dysfunction
  • Congenital heart defect
  • Left atrial myxoma
  • Pulmonary embolism
  • Cardiac arrhythmias

Reflex causes

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Other causes

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Causes of nocturnal TLOC

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References

  1. Petkar S, Cooper P, Fitzpatrick AP. How to avoid a misdiagnosis in patients with transient loss of consciousness. Postgrad Med J 2006; 82:630-641.
  2. Brignole M, Moya A, de Lange FJ, et al; ESC Scientific Document Group. 2018 ESC Guidelines for the diagnosis and management of syncope. Eur Heart J 2018; 39:1883-1948.
  3. Marrison VK, Parry SW. A case of nocturnal fainting: supine vasovagal syncope. Europace 2007; 9:835-836.
  4. Raj PL, Sheldon RS, Lorenzetti D, Jardine DL, Raj SR, Vandenberk B. Sleep syncope - a systematic review. Front Cardiovasc Med 2022; 9:973368. 

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