Toxoplasmosis: clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Toxoplasmosis: clinical features. Toxoplasma gondii is the causative parasite, Transmission may also be congenital. Fully referenced neurology checklist.

Biology

  • Toxoplasma gondii is the causative parasite
  • Transmission of T. gondii cysts is food borne via raw meat, and water-borne via cat faeces
  • Transmission may also be congenital

Maturation forms

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Risk factors for infection and reactivation

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Encephalitic features

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Other neurological features

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Ocular toxoplasmosis

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Congenital toxoplasmosis: features

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Congenital toxoplasmosis: differentials (TORCH complex)

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Other features

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References

  1. Dzikowiec M, Góralska K, Błaszkowska J. Neuroinvasions caused by parasites. Ann Parasitol 2017; 63:243–253.
  2. Furtado JM, Smith JR, Belfort R Jr, Gattey D, Winthrop KL. Toxoplasmosis: a global threat. J Glob Infect Dis 2011; 3:281-284. 
  3. Wohlfert EA, Blader IJ, Wilson EH. Brains and brawn: toxoplasma infections of the central nervous system and skeletal muscle. Trends Parasitol 2017; 33:519-531. 
  4. Paspalaki PK, Mihailidou EP, Bitsori M, Tsagkaraki D, Mantzouranis E. Polyomyositis and myocarditis associated with acquired toxoplasmosis in an immunocompetent girl. BMC Musculoskelet Disord 2001; 2:8.
  5. Bosch-Driessen LE, Berendschot TT, Ongkosuwito JV, Rothova A. Ocular toxoplasmosis: clinical features and prognosis of 154 patients. Ophthalmology 2002; 109:869-878.

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