Tourette syndrome: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Tourette syndrome: clinical features. Mutations of the ASH1L gene may confer susceptibility. Fully referenced neurology checklist.
Genetics
- Mutations of the ASH1L gene may confer susceptibility
Types
Locked: subscribe to see this section.
Onset age
Locked: subscribe to see this section.
Clinical features
Locked: subscribe to see this section.
Diagnostic criteria
Locked: subscribe to see this section.
Co-morbidities
Locked: subscribe to see this section.
Features of adult Tourette syndrome
Locked: subscribe to see this section.
Features suggestive of TS against secondary tic disorders
Locked: subscribe to see this section.
Pathological features
Locked: subscribe to see this section.
References
- Cath DC, Hedderly T, Ludolph AG, et al. European clinical guidelines for Tourette syndrome and other tic disorders. Part I: assessment. Eur Childs Adolesc Psychiatry 2011; 20:155-171.
- Liu S, Tian M, He F, et al. Mutations in ASH1L confer susceptibility to Tourette syndrome. Mol Psychiatry 2019; doi: 10.1038/s41380-019-0560-8 (Epub ahead of print).
- Delorme C, Salvador A, Valabrègue R, et al. Enhanced habit formation in Gilles de la Tourette syndrome. Brain 2016; 139:605-615.
- Hirschtritt ME, Darrow SM, Illmann C, et al; Tourette Syndrome Association International Consortium for Genetics (TSAICG). Social disinhibition is a heritable subphenotype of tics in Tourette syndrome. Neurology 2016; 87:497-504.
- Cavanna AE, Ali F, Leckman JF, Robertson MM. Pathological laughter in Gilles de la Tourette syndrome: an unusual phonic tic. Mov Disord 2010; 25:2233-2239.
- And 4 more. Subscribe to see the full list
