Thalamic aphasia syndrome

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Thalamic aphasia syndrome. This is caused by disconnection of cortical language areas from the thalamic nuclei. Fully referenced neurology checklist.

Pathology

  • This is caused by disconnection of cortical language areas from the thalamic nuclei 
  • The lesion is usually in the dominant thalamus or supplementary motor region (SMR)
  • It is worse with left sided lesions

Language impairments

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Clinical features

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Preserved language functions

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References

  1. Jonas S. The thalamus and aphasia, including transcortical aphasia: a review. J Commun Disord 1982; 15:31-41.
  2. Afzal U, Farooq MU. Teaching neuroimages: thalamic aphasia syndrome. Neurology 2013; 81:e177. 
  3. Gorelick PB, Hier DB, Benevento L, Levitt S, Tan W. Aphasia after left thalamic infarction. Arch Neurol 1984; 41:1296-1298.
  4. Fritsch M, Rangus I, Nolte CH. Thalamic aphasia: a review. Curr Neurol Neurosci Rep 2022; 22:855-865.
  5. Rangus I, Fritsch M, Endres M, Udke B, Nolte CH. Frequency and phenotype of thalamic aphasia. J Neurol 2021 (Online ahead of print).

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