Systemic vasculitic peripheral neuropathy (PN): investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Systemic vasculitic peripheral neuropathy (PN): investigations. Full blood count (FBC), Eosinophils. Fully referenced neurology checklist.
Basic investigations
- Full blood count (FBC)
- Eosinophils
- Erythrocyte sedimentation rate (ESR)
- C-reactive protein (CRP)
- Fasting glucose
- HbA1C
- Renal and liver function tests
- Urinalysis
- Rheumatoid factor (RF)
- Protein electrophoresis
Autoantibodies
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Infection screen
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Other blood tests
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Genetic tests
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Imaging
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Nerve biopsy: predictors of positive findings
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Other tests
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References
- Collins MP, Dyck JB, Gronseth GS, et al. Peripheral Nerve Society guideline on the classification, diagnosis, investigation, and immunosuppressive therapy of non-systemic vasculitic neuropathy: executive summary. J Peripher Nerv Syst 2010; 15:176-184.
- Gorson KC. Therapy for vasculitic neuropathies. Curr Treat Options Neurol 2006; 8:105-117.
- Gorson KC. Vasculitic neuropathies: an update. Neurologist 2007; 13:12-19.
- Goedee HS, van der Pol, WL, van Asseldonk J-T H, et al. Nerve sonography to detect peripheral nerve involvement in vasculitis syndromes. Neurol Clin Pract 2016; 6:293-303.
- Nathani D, Barnett MH, Spies J, Pollard J, Wang MX, Kiernan MC. Vasculitic neuropathy: comparison of clinical predictors with histopathological outcome. Muscle Nerve 2019; 59:643-649.
