Spasticity: treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Spasticity: treatment. Baclofen: 5mg tid, Dantrolene: 25mg daily, Tizanidine: 2-4mg tid, Diazepam: 2-5mg bid. Fully referenced neurology checklist.
Anti-spasticity muscle relaxants
- Baclofen: 5mg tid
- Dantrolene: 25mg daily.
- Tizanidine: 2-4mg tid
- Diazepam: 2-5mg bid
- Clonazepam: 0.5mg
- Gabapentin: 100mg
Anti-spasmodic muscle relaxants
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Other muscle relaxants
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Intrathecal agents
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Other treatments
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References
- Ghai A, Garg N, Hooda S, Gupta T. Spasticity - pathogenesis, prevention and treatment strategies. Saudi J Anaesth 2013; 7:453-460.
- Cashin AG, Folly T, Bagg MK, et al. Efficacy, acceptability, and safety of muscle relaxants for adults with non-specific low back pain: systematic review and meta-analysis. BMJ 2021; 374:n1446.
- See S. Ginzburg R. Skeletal muscle relaxants. Pharmacotherapy 2008; 28:207-213.
- Elenbaas JK. Centrally acting oral skeletal muscle relaxants. Am J Hosp Pharm 1980; 37:1313-1323.
