SMART syndrome: management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

SMART syndrome: management. These are focal or regional. Fully referenced neurology checklist.

Magnetic resonance imaging (MRI) brain: cortical thickening

  • These are focal or regional
  • They appear as <5 mm hypodensities on susceptibility weighted imaging (SWI)
  • They are usually in the temporal, parietal, or occipital lobes
  • They spare the white matter
  • They demonstrate linear gadolinium enhancement

Magnetic resonance imaging (MRI) brain: other features

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Electroencephalogram (EEG): features

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Transcranial Doppler ultrasound

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Magnetic resonance spectroscopy (MRS): features

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CT perfusion

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Acute treatment

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Prophylactic treatments

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Acronym

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References

  1. Jaraba S, Puig O, Miró J, et al. Refractory status epilepticus due to SMART syndrome. Epilepsy Behav 2015; 49:189-192. 
  2. Goldfinch AI, Kleinig TJ. Stroke-like migraine attacks after radiation therapy syndrome: a case report and literature review. Radiol Case Rep 2017; 12:610-614.
  3. Olsen AL, Miller JJ, Bhattacharyya S, Voinescu PE, Klein JP. Cerebral perfusion in stroke-like migraine attacks after radiation therapy syndrome. Neurology 2016; 86:787-789. 
  4. Khanipour Roshan S, Salmela MB, McKinney AM. Susceptibility-weighted imaging in stroke-like migraine attacks after radiation therapy syndrome. Neuroradiology 2015; 57:1103-1109.
  5. Serlin Y, Alshahrani M, Frauscher B. Provocative hyperventilation in a patient with stroke-like migraine attacks after radiation therapy. JAMA Neurol 2022; 79:526-527.
  6. And 9 more. Subscribe to see the full list

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