Serotonin syndrome: causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Serotonin syndrome: causes. Selective serotonin reuptake inhibitors (SSRIs). Fully referenced neurology checklist.

Antidepressants

  • Selective serotonin reuptake inhibitors (SSRIs)
  • Serotonin norepinephrine reuptake inhibitors (SNRIs)
  • Tricyclic antidepressants
  • Trazodone
  • Buspirone
  • Lithium

Monoamine oxidase inhibitors (MAOI)

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Anti-emetics and antihistamines

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Abuse drugs

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Opiates

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Other drugs

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References

  1. Munhoz RP, Moscovich M, Araujo PD, Tieve HAG. Movement disorders emergencies: a review. Arq Neuropsiquiatr 2012; 70:453-461.
  2. Frank C. Recognition and treatment of serotonin syndrome. Can Fam Physician 2008; 54:988-992. 
  3. Volpi-Abadie J, Kaye AM, Kaye AD. Serotonin syndrome. Ochsner J 2013; 13:533-540.
  4. Werneke U, Jamshidi F, Taylor DM, Ott M. Conundrums in neurology: diagnosing serotonin syndrome-a meta-analysis of cases. BMC Neurol 2016; 16:97.

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