Sensory neuronopathy: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Sensory neuronopathy: management. Vitamin B12 and Cu deficiency therefore need to be excluded. Fully referenced neurology checklist.
Magnetic resonance imaging (MRI) spine
- There are high T2 signal changes in the posterior columns of the spinal cord
- Vitamin B12 and Cu deficiency therefore need to be excluded
Nerve conduction studies (NCV)
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Skin biopsy
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Neuromuscular ultrasound
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Treatment: of primary cause
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Treatment: immunotherapy
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Synonyms
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References
- Sheikh SI, Amato AA. The dorsal root ganglion under attack: the acquired sensory ganglionopathies. Pract Neurol 2010; 10:326-334.
- Gwathmey KG Sensory neuronopathies. Muscle Nerve 2016; 53:8-19.
- Camdessanche JP, Jousserand G, Ferraud K, et al. The pattern and diagnostic criteria of sensory neuronopathy: a case-control study. Brain 2009; 132:1723-1733.
- Provitera V, Gibbons CH, Wendelschafer-Crabb G, et al. The role of skin biopsy in differentiating small-fiber neuropathy from ganglionopathy. Eur J Neurol 2018; 25:848-853.
- Pelosi L, van Alfen N. Neuromuscular ultrasound as a marker for inherited sensory neuronopathy. Muscle Nerve 2023 (Online ahead of print).
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