Seizure-induced reversible MRI abnormalities (SMRA)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Seizure-induced reversible MRI abnormalities (SMRA). These are usually transient lesions. Fully referenced neurology checklist.

Background

  • These are usually transient lesions
  • They may be unilateral or bilateral
  • They do not conform to vascular territories
  • They may be associated with EEG abnormalities

Risk factors

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Pathophysiology

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Locations

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Composite patterns

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Radiological features

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Resolution

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Differential diagnosis

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Complications

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Synonyms

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Acronym

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References

  1. Williams J, Mullins G, Delanty N, Peter B, Doherty CP. The spectrum of peri-ictal MRI changes; four illustrative cases. Seizure 2017; 50:189-193. 
  2. Williams JA, Bede P, Doherty CP. An exploration of the spectrum of peri-ictal MRI change; a comprehensive literature review. Seizure 2017; 50:19-32.
  3. Szabo K, Poepel A, Pohlmann-Eden B, et al. Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus. Brain 2005; 128:1369-1376.
  4. Cianfoni A, Caulo M, Cerase A, et al. Seizure-induced brain lesions: a wide spectrum of variably reversible MRI abnormalities. Eur J Radiol 2013; 82:1964-1972. 
  5. Lansberg MG, O'Brien MW, Norbash AM, Moseley ME, Morrell M, Albers GW. MRI abnormalities associated with partial status epilepticus. Neurology 1999; 52:1021-1027.
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