Reversible cerebral vasoconstriction syndrome (RCVS): treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Reversible cerebral vasoconstriction syndrome (RCVS): treatment. Discontinue triggering agents. Fully referenced neurology checklist.

Treatment

  • Discontinue triggering agents
  • Calcium channel blockers: Nimodipine, Nifedipine, or Verapamil
  • Steroids: these are controversial as they may worsen RCVS

Treatment of refractory cases

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References

  1. Ducros A, Boukobza M, Porcher R, Sarov M, Valade D, Bousser MG. The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome: a prospective sites of 67 patients. Brain 2007; 130:3091-3101.
  2. Ducros A, Bousser MG. Reversible cerebral vasoconstriction syndrome. Pract Neurol 2009; 9:256-267.
  3. Sattar A, Manousakis G, Jensen MB. Systematic review of reversible cerebral vasoconstriction syndrome. Expert Rev Cardiovasc Ther 2010; 8:1417-1421.
  4. Singhal AB, Topcuoglu MA. Glucocorticoid-associated worsening in reversible cerebral vasoconstriction syndrome. Neurology 2016; 88:228-236.
  5. Bouchard M, Verreault S, Gariépy JL, Dupré N. Intra-arterial milrinone for reversible cerebral vasoconstriction syndrome. Headache 2009; 49:142-145.
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