Refractory epilepsy: interventional treatments
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Refractory epilepsy: interventional treatments. The anterior nucleus of the thalamus: this is the only FDA-approved target. The hippocampus.
Deep brain stimulation (DBS): targets
- The anterior nucleus of the thalamus: this is the only FDA-approved target
- The hippocampus
- The centromedian nucleus
Deep brain stimulation (DBS): benefits
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Other forms of neurostimulation
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Epilepsy surgery
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Other interventions
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Synonyms
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References
- Beleza P. Refractory epilepsy: a clinically oriented review. Eur Neurol 2009; 62: 65-71.
- Krauss GL, Sperling MR. Treating patients with medically resistant epilepsy. Neurol Clin Pract 2011; 1: 14-22.
- Yassin A, Al-Kraimeen L, Qarqash A, et al. Deep brain stimulation targets in drug-resistant epilepsy: Systematic review and meta-analysis of effectiveness and predictors of response. Seizure 2024; 122:144-152.
- Chabardès S, Bartolomei F, Nica A, et al. Deep brain stimulation of the thalamus for intractable epilepsy (FRANCE study): a randomized clinical trial. Epilepsia 2026; 67:3318-3330.
- Li MCH, Cook MJ. Deep brain stimulation for drug-resistant epilepsy. Epilepsia. 2018; 59:273-290.
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