Radiation necrosis v tumour recurrence
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Radiation necrosis v tumour recurrence. Enhancement, Oedema, Mass effect, Necrosis, Cavitation. Fully referenced neurology checklist.
Features common to radiation necrosis and tumour recurrence
- Enhancement
- Oedema
- Mass effect
- Necrosis
- Cavitation
- Hypermetabolism: on positron emission tomography (PET) scans
Features of tumour recurrence
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Features of radiation necrosis
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References
- Ricci PE, Karis JP, Heisetman JE, Fram EK, Bice AN, Drayer BP. Differentiating recurrent tumour from radiation necrosis: time for re-evaluation of positron emission tomography? Am J Neuroradiol 1998; 19:407-413.
- Mullins ME, Barest GD, Schaefer PW, Hochberg FH, Gonzalez RG, Lev MH. Radiation necrosis versus glioma recurrence: conventional MR imaging clues to diagnosis. Am J Neuroradiol 2005; 26:1967-1972.
- Weybright P, Sundgren PC, Maly P, et al. Differentiation between brain tumour recurrence and radiation injury using MR spectroscopy. Am J Roentgenol 2005; 185:1471-1476.
- Grossman RI, Yousem DM. The requisites Neuroradiology. 2nd edition. Mosby Philadelphia 2003 p169.
- Zakhari N, Taccone MS, Torres C, et al. Diagnostic accuracy of centrally restricted diffusion in the differentiation of treatment-related necrosis from tumor recurrence in high-grade gliomas. Am J Neuroradiol 2018; 39:260-264.
