Radiation induced toxicity: pathology and risk factors

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Radiation induced toxicity: pathology and risk factors. Ischaemia from damage to blood vessels, Direct nerve damage. Fully referenced neurology checklist.

Pathology of radiation damage

  • Ischaemia from damage to blood vessels
  • Direct nerve damage
  • Fibrosis of tissues

Affected tissues

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Genetic risk factors

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Other risk factors

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References

  1. Stubblefield MD. Radiation fibrosis syndrome: neuromuscular and musculoskeletal complications in cancer survivors. PM R 2011; 3:1041-1054.
  2. Delanian S, Lefaix JL, Pradat PF. Radiation-induced neuropathy in cancer survivors. Radiother Oncol 2012; 105:273-282.
  3. Straub JM, New J, Hamilton CD, Lominska C, Shnayder Y, Thomas SM. Radiation-induced fibrosis: mechanisms and implications for therapy. J Cancer Res Clin Oncol 2015; 141:1985-1994.

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