Rabies encephalitis: treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Rabies encephalitis: treatment. Relatives, Staff, Animal handlers, Laboratory workers, Travellers. Fully referenced neurology checklist.

Pre-exposure vaccination: indications

  • Relatives
  • Staff
  • Animal handlers
  • Laboratory workers
  • Travellers

General treatment

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Sedation

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Milwaukee protocol

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Antiviral treatment

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References

  1. Hemachudha T, Ugolini G, Wacharapluesadee S, Sungkarat W, Shuangshoti S, Laothamatas J. Human rabies: neuropathogenesis, diagnosis, and management. Lancet Neurol 2013; 12:498-513. 
  2. Yousaf MZ, Qasim M, Zia S, Khan M, Ashfaq UA, Khan S. Rabies molecular virology, diagnosis, prevention and treatment. Virol J 2012; 9:50.
  3. Hemachudha P, Hemachudha T. Rabies: presentation, case management and therapy. J Neurol Sci 2021; 424:117413.
  4. Jackson AC. Demise of the Milwaukee protocol for rabies. Clin Infect Dis 2025 (Online ahead of print).
  5. Awasthi M, Parmar H, Patankar T, Castillo M. Imaging findings in rabies encephalitis. AJNR 2001; 22:677-680.

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