Primary hyperparathyroidism

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Primary hyperparathyroidism. Hyperthyroid adenoma, Multiple endocrine neoplasia (MEN). Fully referenced neurology checklist.

Causes

  • Hyperthyroid adenoma
  • Multiple endocrine neoplasia (MEN)
  • Hyperparathyroid-jaw tumour syndrome

Central neurological features

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Peripheral neurological features

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Psychiatric features

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Constitutional features

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Systemic features

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Biochemical features

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Differential diagnosis

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References

  1. Walker MD, Silverberg SJ. Primary hyperparathyroidism. Nat Rev Endocrinol 2018; 14:115-125. 
  2. Patten BM, Pages M. Severe neurological disease associated with hyperparathyroidism. Ann Neurol 1984; 15:453-456.
  3. Roy M, Sahana PK, Sengupta N, Das C, Dasgupta R. An unusual case of episodic quadriparesis. Indian J Endocrinol Metab 2013; 17(Suppl 1):S234-S236.
  4. Cagney D, Razzaq Z, Majeed M, O'Leary DP, Redmond HP. Primary hyperparathyroidism causing posterior reversible encephalopathy syndrome: a case report. Ann R Coll Surg Engl 2021; 103:e341-e344.
  5. Pal R, Dutta A, Agrawal K, Jain N, Dutta P, Bhansali A, Behera A, Bhadada SK. Primary hyperparathyroidism presenting as posterior reversible encephalopathy syndrome: a report of two cases. J Clin Res Pediatr Endocrinol 2020; 12:432-438.
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