Primary angiitis of the central nervous system (PACNS): differential against RCVS
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Primary angiitis of the central nervous system (PACNS): differential against RCVS. Recurrent thunderclap headache (TCH), Use of vasoactive substances.
Predictors of RCVS against PACNS
- Recurrent thunderclap headache (TCH)
- Use of vasoactive substances
- History of migraine
- Normal imaging
- Border zone infarcts
- Vasogenic edema
- Subarachnoid haemorrhage (SAH)
- Cervical artery dissection
- Normal angiography
- Absence of focal signs
- Low RCVS2 score
Predictors of PACNS against RCVS
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Acronym
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References
- de Boysson H, Parienti JJ, Mawet J, et al. Primary angiitis of the CNS and reversible cerebral vasoconstriction syndrome: a comparative study. Neurology 2018; 91:e1468-e1478.
- Singhal AB, Topcuoglu MA, Fok JW, Kursun O, Nogueira RG, Frosch MP, Caviness VS Jr. Reversible cerebral vasoconstriction syndromes and primary angiitis of the central nervous system: clinical, imaging, and angiographic comparison. Ann Neurol 2016; 79:882-894.
- Rocha EA, Topcuoglu MA, Silva GS, Singhal AB. RCVS2 score and diagnostic approach for reversible cerebral vasoconstriction syndrome. Neurology 2019; 92:e639-e647.