Pregnancy and myotonic dystrophy

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Pregnancy and myotonic dystrophy. There is reduced male fertility. There is reduced ovarian reserve. Fully referenced neurology checklist.

Effect of myotonic dystrophy type 1 on fertility

  • There is reduced male fertility
  • There is reduced ovarian reserve

Effect of myotonic dystrophy type 1 on pregnancy

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Effect of myotonic dystrophy type 2 on pregnancy

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Preconception management

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Pregnancy management

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Post-partum management

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References

  1. Ashizawa T, Gagnon C, Groh WJ, et al. Consensus-based care recommendations for adults with myotonic dystrophy type 1. Neurol Clin Pract 2018; 8:507-520.
  2. Srebnik N, Margalioth EJ, Rabinowitz R, et al. Ovarian reserve and PGD treatment outcome in women with myotonic dystrophy. Reprod Biomed Online 2014; 29:94-101.
  3. Johnson NE, Hung M, Nasser E, Hagerman KA, Chen W, Ciafaloni E, Heatwole CR. The impact of pregnancy on myotonic dystrophy: A Registry-based study. J Neuromuscul Dis 2015; 2:447-452.
  4. Rudnik-Schöneborn S, Nicholson GA, Morgan G, Röhrig D, Zerres K. Different patterns of obstetric complications in myotonic dystrophy in relation to the disease status of the fetus. Am J Med Genet 1998; 80:314-321.
  5. Rudnik-Schöneborn S, Zerres K. Outcome in pregnancies complicated by myotonic dystrophy: a study of 31 patients and review of the literature. Eur J Obstet Gynecol Reprod Biol 2004; 114:44-53.
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