Post-polio syndrome (PPS): clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Post-polio syndrome (PPS): clinical features. This is the development of new muscle weakness and fatigue in people with polio.

Definition

  • This is the development of new muscle weakness and fatigue in people with polio
  • It sets in 15-30 years after the acute paralytic episode

Potential causes

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Risk factors

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Neurological features

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Psychiatric features

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Systemic features

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Complications

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References

  1. Gonzalez H, Olsson T, Borg K. Management of postpolio syndrome. Lancet Neurol 2010; 9:634-642.
  2. Farbu E, Gilhus NE, Barnes MP, et al. EFNS guideline on diagnosis and management of post-polio syndrome. Report of an EFNS task force. Eur J Neurol 2006; 13:795-801.
  3. Punsoni M, Lakis NS, Mellion M, de la Monte SM. Post-polio syndrome revisited. Neurol Int 2023; 15:569-579. 
  4. Trojan DA, Cashman NR, Shapiro S, Tansey CM, Esdaile JM. Predictive factors for post-poliomyelitis syndrome. Arch Phys Med Rehabil 1994; 75:770-777.
  5. McNalley TE, Yorkston KM, Jensen MP, et al. Review of secondary health conditions in postpolio syndrome: prevalence and effects of aging. Am J Phys Med Rehabil 2015; 94:139-145. 
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