Pathological hiccups: management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Pathological hiccups: management. Baclofen, Gabapentin, Chlorpromazine, Carbamazepine, Metoclopramide, Haloperidol. Fully referenced neurology checklist.

Drug treatments

  • Baclofen
  • Gabapentin
  • Chlorpromazine
  • Carbamazepine
  • Metoclopramide
  • Haloperidol
  • Amitriptyline
  • Lidocaine
  • Nimodipine
  • Valproate

Respiratory manoeuvres

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Nasopharyngeal stimulation

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Vagus nerve stimulation

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Stomach evacuation

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Phrenic nerve calming techniques

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Psychological treatments

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Other treatments

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References

  1. Eisenacher A, Spiske J. Persistent hiccups (singultus) as the presenting symptom of medullary cavernoma. Dtsch Arztebl Int 2011; 108:822-826.
  2. Launois S, Bizec JL, Whitelaw WA, Cabane J, Derenne JPh. Hiccup in adults: an overview. Eur Respir J 1993; 6:563-575.
  3. Lance J, Bassil GT. Familial intractable hiccup relieved by Baclofen. Lancet 1989; 8657:276-277.

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