Paraneoplastic neurological syndromes: classification

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Paraneoplastic neurological syndromes: classification. Paraneoplastic encephalitis, Brainstem encephalitis. Fully referenced neurology checklist.

Paraneoplastic encephalitis

  • Paraneoplastic encephalitis
  • Brainstem encephalitis
  • Encephaloneuromyelitis
  • Limbic encephalitis
  • Rapidly progressive cerebellar syndrome (RPCS)
  • Opsoclonus-myoclonus syndrome (OMS)

Paraneoplastic myelopathies

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Paraneoplastic ophthalmic syndromes

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Paraneoplastic ophthalmic syndromes with ophthalmic involvement

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Paraneoplastic autonomic syndromes

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Paraneoplastic neuromuscular junction (NMJ) syndromes

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Paraneoplastic myopathies

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Paraneoplastic neuropathies

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Paraneoplastic cochleovestibulopathy (PCVP)

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Other paraneoplastic neurological syndromes

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References

  1. Vaišvilas M, Ciano-Petersen NL, Macarena Villagrán-García MD, Muñiz-Castrillo S, Vogrig A, Honnorat J. Paraneoplastic encephalitis: clinically based approach on diagnosis and management. Postgrad Med J 2023 (Online ahead of print).
  2. Graus F, Delattre JY, Antoine, et al. Recommended diagnostic criteria for paraneoplastic neurological syndromes. JNNP 2004; 75:1235-1240.
  3. Rosenfeld MR, Dalmau J. Update on paraneoplastic neurologic disorders. Oncologist 2010; 15:603-617.
  4. Jarius S, Wildemann B. 'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII. J Neuroinflammation 2015; 12:166. 
  5. Jarius S, Wildemann B. ‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma, anti-GluR-delta2, anti-Ca/ARHGAP26 and anti-VGCC. J Neuroinflammation 2015; 12:167. 
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