Orthostatic tremor (OT): treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Orthostatic tremor (OT): treatment. Clonazepam: this is the first line treatment, Gabapentin, Levodopa, Primidone. Fully referenced neurology checklist.

Drug treatments

  • Clonazepam: this is the first line treatment
  • Gabapentin
  • Levodopa
  • Primidone
  • Phenobarbital
  • Pramipexole
  • Acetazolamide: this is effective in some cases
  • Propranolol and alcohol are not effective

Interventional treatments

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References

  1. Jones L, Bain PG. Orthostatic tremor. Pract Neurol 2011; 11:240-243.
  2. Mestre TA, Lang AE, Ferreira JJ, et al. Associated movement disorders in orthostatic tremor. JNNP 2012; 83:725-729.
  3. Guridi J, Rodriguez-Oroz MC, Arbizu J, et al. Successful thalamic deep brain stimulation for orthostatic tremor. Mov Disord 2008; 23:1808-1811.
  4. Blahak C, Sauer T, Baezner H, et al. Long-term follow-up of chronic spinal cord stimulation for medically intractable orthostatic tremor. J Neurol 2016; 263:2224-2228.

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