Optic neuritis: clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Optic neuritis: clinical features. Onset age is usually < 50 years. There is subacute unilateral visual impairment. Fully referenced neurology checklist.

Onset and progression

  • Onset age is usually < 50 years
  • There is subacute unilateral visual impairment
  • It is progressive over days
  • Improvement occurs after 2-3 weeks

Features of eye pain

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Other symptoms

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Relative apparent pupillary defect (RAPD)

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Uhthoff’s phenomenon

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Pulfrich phenomenon

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Fundoscopy

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Other features

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Differential diagnosis

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Treatment

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References

  1. Voss E, Raab P, Trebst C, Stangel M. Clinical approach to optic neuritis: pitfalls, red flags and differential diagnosis. Ther Adv Neurol Disord 2011; 4:123-134.
  2. Hoorbakht H, Bagherkashi F. Optic neuritis, its differential diagnosis and management. Open Ophthalmol J 2012; 6:65-72.
  3. Foroozan R, Buono LM, Savino PJ, Sergott RC. Acute demyelinating optic neuritis. Curr Opin Ophthalmol 2002; 13:375-380.
  4. Shams PN, Plant GT. Optic neuritis: a review. Int MS J 2009; 16:82-89.
  5. Behbehani R. Clinical approach to optic neuropathies. Clin Ophthalmol 2007; 1:233-246.
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