Ocular neuromyotonia

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Ocular neuromyotonia. This is recurrent spontaneous spasms of the extraocular muscles. Fully referenced neurology checklist.

Clinical features

  • This is recurrent spontaneous spasms of the extraocular muscles
  • The episodes cause tonic deviation of the eyes
  • They may occur bilaterally
  • They last seconds to minutes
  • They recur every 10-40 minutes throughout the day
  • They result in intermittent or paroxysmal gaze-evoked diplopia
  • They may be associated with internuclear ophthalmoplegia (INO)
  • They may also cause spastic eye closure

Causes

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Triggers

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Differential diagnosis

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Investigation

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Treatment

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References

  1. Gold DR. Teaching NeuroImages: Ocular neuromyotonia. An underrecognized cause of transient diplopia. Neurology 2016; 86:e249.
  2. Kuroda M, Isozaki E, Matsubara S, Yoshida H, Hayashi H. Case of ocular neuromyotonia with transient and gaze-induced diplopia. Rinsho Shinkeigaku 2007; 47:344-347. 
  3. Ezra E, Spalton D, Sanders MD, Graham EM, Plant GT. Ocular neuromyotonia. Br J Ophthalmol 1996; 80:350-355.
  4. Roper-Hall G, Chung SM, Cruz OA. Ocular neuromyotonia: differential diagnosis and treatment. Strabismus 2013; 21:131-136. 
  5. Soares-Dos-Reis R, Martins AI, Brás A, Matos A, Bento C, Lemos J. Ocular neuromyotonia. Pract Neurol 2018; 18:389-390. 
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