Neurosarcoidosis: other investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Neurosarcoidosis: other investigations. Calcium: this is raised in 10% of cases, CD4:CD8 ratio: this is >3.5. Fully referenced neurology checklist.
Blood tests
- Calcium: this is raised in 10% of cases
- Angiotensin converting enzyme (ACE): this is high in about 30% of cases
- CD4:CD8 ratio: this is >3.5
Chest imaging tests
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Tissue samples
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Other tests
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References
- Joseph FG, Scolding NJ. Neurosarcoidosis: a study of 30 new cases. JNNP 2009; 80:297-304.
- Joseph FG, Scolding NJ. Sarcoidosis of the central nervous system. Pract Neurol 2007; 7:234-244.
- Sun Q, Lu X, Xiao X, et al. Tiger man sign in sarcoid myopathy. Neurology 2025; 105:e214323.
- Pruthi A, Kirtani P, Joshi P, Kaur N. Tiger man sign-F-18 FDG PET CT scan pattern in muscular and cutaneous sarcoidosis: a case report and literature survey. Indian J Nucl Med 2020; 35:232-234.
- Dierks A, Kircher M, Schmid SJ, Kramer D, Buck AK, Lapa C. Tiger man sign in sarcoid myopathy. Eur J Nucl Med Mol Imaging 2019; 46:1039-1040.
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