Neuroleptospirosis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Neuroleptospirosis. Leptospirosis is caused by Leptospiral interrogans. Fully referenced neurology checklist.
Pathology
- Leptospirosis is caused by Leptospiral interrogans
- It is transmitted by urine of animals: especially rats and mice
- It causes vasculitic and immune-mediated damage
Systemic features
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Cardiorespiratory features
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Gastrointestinal features
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Ophthalmic features
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Central neurological phenotypes
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Central neurological features
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Peripheral neurological phenotypes
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Other features
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Differential diagnosis
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Poor prognostic features
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Magnetic resonance imaging (MRI) brain: features
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Cerebrospinal fluid (CSF) analysis
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Other investigations
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Treatment
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References
- Mathew T, Satishchandra P, Mahadevan A, et al. Neuroleptospirosis - revisited: experience from a tertiary care neurological centre from south India. Indian J Med Res 2006; 124:155-162.
- Datta S, Sarkar RN, Biswas A, Mitra S. Leptospirosis: an institutional experience. J Indian Med Assoc 2011; 109:737-738.
- Panicker JN, Mammachan R, Jayakumar RV. Primary neuroleptospirosis. Postgrad Med J 2001; 77:589-590.
- Courtin JP, Di Francia M, Du Couëdic I, et al. Respiratory manifestations of leptospirosis. A retrospective study of 91 cases (1978-1984). Rev Pneumol Clin 1998; 54:382-392.
- Abgueguen P, Delbos V, Blanvillain J, et al. Clinical aspects and prognostic factors of leptospirosis in adults. Retrospective study in France. J Infect 2008; 57:171-178.
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