Neuroleptic malignant syndrome (NMS): management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Neuroleptic malignant syndrome (NMS): management. Raised creatinine kinase (CK), Leucocytosis, Rhabdomyolysis. Fully referenced neurology checklist.

Investigations

  • Raised creatinine kinase (CK)
  • Leucocytosis
  • Rhabdomyolysis
  • Renal impairment
  • Abnormal liver function
  • Abnormal coagulation

Treatment of rigidity

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Treatment of excessive dopaminergic block

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Non-drug treatments

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References

  1. Adnet P, Lestavel P, Krivosic-Horber R. Neuroleptic malignant syndrome. Br J Anaesth 2000; 85:129-135.
  2. Munhoz RP, Moscovich M, Araujo PD, Tieve HAG. Movement disorders emergencies: a review. Arq Neuropsiquiatr 2012; 70:453-461.
  3. Strawn JR, Keck PE Jr, Caroff SN. Neuroleptic malignant syndrome. Am J Psychiatry 2007; 164:871-876.

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