Myogenic tremor
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Myogenic tremor. This is tremor that arises from muscles. Fully referenced neurology checklist.
Pathology
- This is tremor that arises from muscles
- It is seen in myopathies that affect the contractile elements of muscle
- It is generated from the sarcomere
- It may be caused by mutations in sarcomeric genes
- It is a high frequency, postural, and kinetic tremor
Genetic causes
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Acquired causes
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References
- Schaefer J, Saak A, Bönnemann CG, Jackson S. Myogenic tremor - a novel tremor entity. Curr Opin Neurol 2021; 34:706-713.
- Stavusis J, Geist J, Kontrogianni-Konstantopoulos A. Sarcomeric myopathies associated with tremor: new insights and perspectives. J Muscle Res Cell Motil 2020; 41:285-295.
- Vial F, McGurrin P, Osterholt T, et al. Electrophysiological characterization of a MYH7 variant with tremor phenotype. Mov Disord Clin Pract. 2023 Mar 14;10(4):646-651.
- Geist Hauserman J, Stavusis J, Joca HC, et al. Sarcomeric deficits underlie MYBPC1-associated myopathy with myogenic tremor. JCI Insight 2021; 6:e147612.
- Uneoka S, Kobayashi T, Numata-Uematsu Y, et al. A case series of patients with MYBPC1 gene variants featuring undulating tongue movements as myogenic tremor. Pediatr Neurol 2023; 146:16-20.
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