Muscle biopsy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Muscle biopsy. Rapidly progressive muscle weakness, Diagnosis of myopathies. Fully referenced neurology checklist.
Indications
- Rapidly progressive muscle weakness
- Diagnosis of myopathies
- Asymptomatic or minimally symptomatic hyperCKaemia
- Vasculitic neuropathy
- Isolated muscle masses
Choice of muscle site
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Pre-procedural precautions
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Procedural precautions
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Specimen processing
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Stains used
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Disease patterns
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References
- Joyce NC, Oskarsson B, Jin LW. Muscle biopsy evaluation in neuromuscular disorders. Phys Med Rehabil Clin N Am 2012; 23:609-631.
- Meola G, Bugiardini E, Cardani R. Muscle biopsy. J Neurol 2012; 259:601-610.
- Dabby R, Sadeh M, Herman O, et al. Asymptomatic or minimally symptomatic hyperCKemia: histopathologic correlates. Isr Med Assoc J 2006; 8:110-113.
- Vital C, Vital A, Canron MH, et al. Combined nerve and muscle biopsy in the diagnosis of vasculitic neuropathy. A 16-year retrospective study of 202 cases. J Peripher Nerv Syst 2006; 11:20-29.
- Agadi JB, Raghav G, Mahadevan A, Shankar SK. Usefulness of superficial peroneal nerve/peroneus brevis muscle biopsy in the diagnosis of vasculitic neuropathy. J Clin Neurosci 2012; 19:1392-1396.
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