Migraine treatment in pregnancy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Migraine treatment in pregnancy. Metoclopramide is probably safe, Domperidone is probably safe. Fully referenced neurology checklist.
Antiemetics
- Metoclopramide is probably safe
- Domperidone is probably safe
- Ondansteron and Droperidol should be used with caution
- Prochlorperazine is contraindicated
Triptans
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Aspirin
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Other analgesics
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Betablockers
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Other prophylactic drugs
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Contraindicated drugs
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Relatively contraindicated steroids
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References
- MacGregor EA. Migraine in pregnancy and lactation: a clinical review. J Fam Plann Reprod Health Care 2007; 33:83-93.
- Evers S, Afra J, Frese A, et al. EFNS guideline on the drug treatment of migraine-revised report of an EFNS task force. Eur J Neurol 2009; 16:968-981.
- MacGregor EA. Menstrual migraine: therapeutic approaches. Ther Adv Neurol Disord 2009; 2:327-336.
- Sawle GV, Ramsay MM. The neurology of pregnancy. JNNP 1998; 64:711-725.
- Negro A, Delaruelle Z, Ivanova TA, et al; European Headache Federation School of Advanced Studies (EHF-SAS). Headache and pregnancy: a systematic review. J Headache Pain 2017; 18:106.
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