MERRF: treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
MERRF: treatment. Coenzyme Q10, Vitamin B complex, L-carnitine. Fully referenced neurology checklist.
Mitochondrial treatments
- Coenzyme Q10
- Vitamin B complex
- L-carnitine
Treatment of myoclonus
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Treatment of seizures
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Drugs to avoid
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Acronym
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References
- Rahman S, Hanna MG. Diagnosis and therapy in neuromuscular disorders: diagnosis and new treatments in mitochondrial diseases. JNNP 2009; 80:943-953.
- Lorenzoni PJ, Scola RH, Kay CS, Silvado CE, Werneck LC. When should MERRF) myoclonus epilepsy associated with ragged-red fibers) be the diagnosis? Arq Neuropsiquiatr 2014; 72:803-811.
- Finsterer J, Zarrouk-Mahjoub S. Management of epilepsy in MERRF syndrome. Seizure 2017; 50:166-170.
- Finsterer J. A review of the advances in the medical management of epilepsy associated with myoclonic epilepsy with ragged-red fibers (MERRF) syndrome. Cureus 2025; 17:e82875.