Melkersson Rosenthal syndrome
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Melkersson Rosenthal syndrome. Recurrent non-pitting orofacial oedema, Fissured tongue (lingua plicata). Fully referenced neurology checklist.
Cardinal features
- Recurrent non-pitting orofacial oedema
- Fissured tongue (lingua plicata)
- Recurrent lower motor neurone facial palsy
- The features may be unilateral or bilateral
Possible causes
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Possible associated disorders
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Associated features
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Biopsy features of granulomatous cheilitis
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Main treatments
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Treatments based on case reports
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References
- Greene RM, Rogers RS 3rd. Melkersson-Rosenthal syndrome: A review of 36 patients. J Am Acad Dermatol 1989; 21:1263-1270.
- Pimentel S, Mendes A, Rosas MJ. Peripheral facial palsy in the setting of Melkersson-Rosenthal Syndrome-case report. Rev Neurocienc 2012; 20:233-235.
- Pisanty S, Sharav Y. The Melkersson-Rosenthal syndrome. Oral Surg 1969; 27:729-733.
- Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson-Rosenthal Syndrome: new clinicopathologic findings in 4 Cases. Arch Ophthalmol 2000; 118:227-232.
- Pei Y, Beaman GM, Mansfield D, Clayton-Smith J, Stewart M, Newman WG. Clinical and genetic heterogeneity in Melkersson-Rosenthal Syndrome. Eur J Med Genet 2019; 62:103536.
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