Marburg variant multiple sclerosis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Marburg variant multiple sclerosis. This is a fulminant pseudotumour form of multiple sclerosis (MS). Fully referenced neurology checklist.
Pathology
- This is a fulminant pseudotumour form of multiple sclerosis (MS)
- It progresses over weeks to months
- It has a high morbidity and mortality
Clinical features
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Differential diagnosis
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Magnetic resonance imaging (MRI)
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Cerebrospinal fluid (CSF) analysis
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Brain biopsy
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Treatment
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Usually ineffective treatments
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Synonym
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References
- Capet N, Levraut M, Delourme A, et al. Marburg multiple sclerosis variant: complete remission with very early administration of mitoxantrone-a case report. Neurol Ther 2021 (Online ahead of print).
- Elenein RG, Sharer LR, Cook SD, Pachner AR, Michaels J, Hillen ME. A second case of Marburg's variant of multiple sclerosis with vasculitis and extensive demyelination. Mult Scler 2011; 17:1531-1538.
- Manuel A, Vasudevan MC. A case of Marburg's variant of multiple sclerosis successfully treated with IVIg and mitoxantrone. Ann Indian Acad Neurol 2021; 24:92-94.
- Turatti M, Gajofatto A, Rossi F, Vedovello M, Benedetti MD. Long survival and clinical stability in Marburg's variant multiple sclerosis. Neurol Sci 2010; 31:807-811.
- AlOhaly N, Nathoo N, Schmitt LM, McCombe JA Dr. Lymphomatosis cerebri masquerading as the Marburg variant of multiple sclerosis. Mult Scler Relat Disord 2020; 46:102488.
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